Lidocaine Base
Temporarily mouth, throat or nose, digestive tract and to eliminate the pain. Determined by your doctor as it can also be used for other conditions. Nerve transmission of pain impulses from the brain by preventing functions.
Certificate of Analysis
- Description
White or almost white crystalline powder.
Result
Almost white crystalline powder.
- Solubility
Practically insoluble in water, very soluble in ethanol & in methylene chloride.
Result
Complies
- Identification
To comply IR Test.
Result
Complies
- Related Substance
ResultComplies
- Impurity A
NMT 0.01%
Result
Not detected
- Unspecified Impurities
NMT 0.10%
Result
0.0569%
- Total Impurities
NMT 0.5%
Result
0.0946%
- Chloride
NMT 35 PPM
Result
Complies
- Sulphates
NMT 0.1%
Result
Complies
- Water
NMT 1.0% w/w
Result
0.47% w/w
- Sulphated Ash
NMT 0.1% w/w
Result
0.070% w/w
- Assay
NLT 99.0% & NMT 101% of C14H22N2O, on anhydrous basis.
Result
99.51% w/w
Note: We are leading channel partner of much API manufacturer, supplier & exporters and Pharmaceutical raw material in Colombo, Chili, Ecuador and Globally.
Material Safety Data Sheet
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Section 1 – Chemical Product
Product Identifier
Lidocaine Base
MSDS Prepared By
R&D Department
-
Section 2 – Composition / Information Of Ingredients
Product Name
Lidocaine Base
Synonym
2-Diethulamino-N-(2,6-dimethylphenyl)acetamide Lignocaine Xylocaine
Molecular Formula
C14H22N2O
Molecular Weight
234.34 g/mol
CAS Number
137-58-6
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Section 3 – HAZARDOUS IDENTIFICATION
Acute Toxicity Oral
Category 4
Single Word
Warning
Hazard Statement(s)
H302
Harmful if swallowed.
Precautionary Statement
None
Supplemental Hazard
None
R-Phrase(s)
R22
Harmful if swallowed.
S-Phrase(s)
S22
Do not breathe dust.
S26
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36
Wear suitable protective clothing.
Other Hazards
None
-
Section 4 – FIRST AID
General Information
Consult a physician. Show this safety data sheet to the doctor in attendance.
Eye Contact
Flush eyes with water as a precaution.
Skin Contact
Wash off with plenty of water. Consult a physician.
Inhalation
If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
Ingestion
Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.
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Section 5 – FIRE FIGHTING MEASURES
Suitable Extinguishing Media
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazard arising from the Substance or Mixture
Carbon oxides, Nitrogen Oxides (NOx)
Advice for Fire-fighters
Wear self-contaminated breathing apparatus for fire-fighting if necessary.
Further Information
N/A
-
Section 6 – ACCIDENT RELEASE MEASURES
Personal Precaution
Use personal protective equipment. Avoid dust formation. Avoid breathing vapors, mist or gas. Ensure adequate ventilation. Avoid breathing dust.
Environmental Precautions
Do not allow to enter drains.
Methods for Cleaning Up
Pick up and arrange disposal without creating dust. Sweep up and shovel. Keep in suitable, closed containers for disposal.
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Section 7 – HANDLING AND STORAGE
Handling
Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Provide appropriate exhaust ventilation at places where dust is formed. Normal measures for preventive fire protection.
Storage
Store in cool place. Keep container tightly closed in a dry and well-ventilated place.
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Section 8 – EXPOSURE CONTROLS / PERSONAL PROTECTION
Engineering Controls
Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.
Personal Protective Equipment
Eye / Face Protection
Safety glasses with side-shields conforming to EN166 Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin Protection
Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove’s outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands.
Body Protection
Complete suit protecting against chemicals, the type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory Protection
For nuisance exposures use type P95 (US) or type P1 (EU EN 143) particle respirator. For higher level protection use type OV/AG/P99 (US) or type ABEK -P2 (EU EN 143) respirator cartridges. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
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Section 9 – PHYSICAL AND CHEMICAL PROPERITIES
Form
Solid
Odour
N/A
Odour Threshold
N/A
pH
N/A
Melting Point / Freezing Point
Melting Point range 66 – 69° C
Initial Boiling Point
N/A
Flash Point
N/A
Evaporation Rate
N/A
Flammability
N/A
Upper / Lower Flammability
N/A
Vapor Pressure
N/A
Vapor Density
N/A
Relative Density
N/A
Water Solubility
N/A
Partition Coeff.
N/A
Auto-Ignition Temperature
N/A
Decomposition Temperature
N/A
Viscosity
N/A
Explosive Properties
N/A
Oxidizing Properties
N/A
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Section 10 – STABILITY AND REACTIVITY
Reactivity
N/A
Chemical Stability
N/A
Possibility of Hazardous Reactions
N/A
Condition to Avoid
N/A
Incompatible Materials
Strong oxidizing agents
Hazardous Decomposition Product(s)
N/A
-
Section 11 – TOXICOLOGICAL INFORMATION
Acute Toxicity
LD50 Oral [Rat]
317 mg/kg.
Skin Corrosion / Irritation
N/A
Serious Eye Damage / Eye Irritation
N/A
Respiratory or Skin Sensitization
N/A
Germ Cell Mutagenicity
N/A
Carcinogenicity
IARC
No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC
Specific Target Organ toxicity – Single Exposure
N/A
Specific Target Organ toxicity – Repeated Exposure
N/A
Aspiration Hazard
N/A
Potential Health Effects
Eyes
May cause eye irritation.
Skin
May be harmful of absorbed through skin. May cause skin irritation.
Inhalation
May be harmful if inhaled. May cause respiratory tract irritation.
Ingestion
Harmful if swallowed.
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Section 12 – ECOLOGICAL INFORMATION
Toxicity
N/A
Persistence & Degradability
N/A
Bio Cumulative Potential
N/A
Mobility in Soil
N/A
Result of PBT & vPvB assessment
N/A
Other adverse Effects
N/A
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Section 13 – DISPOSAL CONSIDERATION
Product
Offer surplus and non-recyclable solutions to a licensed disposal company. Contact a licensed professional waste disposal service to dispose of this material. Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber.
Contaminated Packaging
Dispose of as unused product.
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Section 14 – TRANSPORT INFORMATION
UN Number
ADR/RID
N/A
IMDG
N/A
IATA
N/A
UN Proper Shipping Name
ADR/RID
Not dangerous good.
IMDG
Not dangerous good.
IATA
Not dangerous good.
Transport Hazard Class(s)
ADR/RID
N/A
IMDG
N/A
IATA
N/A
Packaging Group
ADR/RID
N/A
IMDG
N/A
IATA
N/A
Environmental Hazards
ADR/RID
N/A
IMDG Marine Pollutant
N/A
IATA
N/A
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Section 15 – REGULATORY INFORMATION
No data available.
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Section 16 – OTHER INFORMATION
Global Pharma provides information contained herein in good faith but makes no representation as to its comprehensives or accuracy. This document is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product.
Individuals receiving the information must exercise their independent judgment in determining its appropriateness for a particular purpose.
GLOBAL PHARMA MAKES NO REPRESENTATIONS OR WARRANTIES, EITHER EXPRESSED OR IMPLIED, INCLUDING WITHOUT LIMITATION ANY WARRANTIES OR MERCHANTABILITY, FITNESS FOR A PARTICULER PURPOSE WITH RESPECT TO THE INFORMATION SET FORTH HEREIN OR THE PRODUCT WHICH THE INFORMATION REEFERS. GLOBAL PHARMA WILL NOT BE RESPONSIBLE FOR DAMAGES RESULTING FROM USE OF RELIANCE UPON THIS INFORMATION.